Optical non-invasive diagnostics of microcirculatory-tissue systems of the human body: questions of metrological and instrumentation provision

Evgeny A. Zherebtsov orcid
Orel State University named after I.S. Turgenev, Russia

Victor V. Dremin orcid
Orel State University named after I.S. Turgenev, Russia

Angelina I. Zherebtsova orcid
Orel State University named after I.S. Turgenev, Russia

Irina N. Makovik
Orel State University named after I.S. Turgenev, Russia

Andrey V. Dunaev orcid (Login required)
Orel State University named after I.S. Turgenev, Russia


Paper #3129 received 2016.11.28; accepted for publication 2016.12.29; published online 2016.12.31.

DOI: 10.18287/JBPE16.02.040305

Abstract

Optical techniques are one of the most promising non-invasive technologies for the diagnosis of medical conditions. This work is devoted to the current state of the optical non-invasive diagnostics (OND), especially about instrumentation as well as methodological and metrological provision for this technology. In some details Laser Doppler Flowmetry (LDF) and Fluorescence Spectroscopy (FS) diagnostics methods are considered. The main conclusion is that it is necessary to solve the problems of metrological support OND devices of these types. It is also important to develop a methodology based on diagnostic criteria obtained from a relationship between a number of OND methods and others.

Keywords

optical non-invasive diagnostics; blood microcirculation; biotissue; laser Doppler flowmetry; fluorescence spectroscopy

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