Application of Yb,Er:Glass laser radiation for active drug delivery at the treatment of onychomycosis

Andrey V. Belikov
ITMO University, Saint Petersburg, Russian Federation

Anastasia D. Tavalinskaya (Login required)
ITMO University, Saint Petersburg, Russian Federation

Sergey N. Smirnov
ITMO University, Saint Petersburg, Russian Federation

Andrey N. Sergeev
ITMO University, Saint Petersburg, Russian Federation


Paper #3318 received 15 Jan 2019; revised manuscript received 15 Mar 2019; accepted for publication 23 Mar 2019; published online 30 Mar 2019.

DOI: 10.18287/JBPE19.05.010305

Abstract

The paper discusses the active delivery of a drug (methylene blue solution) through the Er:YLF-laser-perforated nail plate using pulsed radiation of microsecond Yb,Er:Glass laser. Different methods of laser impact on liquid drug are considered: by focused and diverging laser beam. It was established that both discussed methods can provide sufficient dose of the drug for the treatment of onychomycosis.

Keywords

laser; drug delivery; nail; hydrodynamic effects; treatment of onychomycosis; photodynamic therapy

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References


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