Differences in the Effect of 40%-Glucose on the Optical Properties of Healthy and Stromal-Sarcoma Ovaries in Cats

Aleksey A. Selifonov (Login required)
Saratov State University, Russia

Valery V. Tuchin
Saratov State University, Russia
Tomsk State University, Russia
FRC “Saratov Scientific Centre of the Russian Academy of Sciences,” Russia

Paper #8986 received 3 Jun 2023; revised manuscript received 11 Jul 2023; accepted for publication 11 Jul 2023; published online 15 Sep 2023.


Differences in diffuse reflectance and total transmittance of healthy and sarcoma cat ovarian tissue were determined using integrating sphere spectroscopy and confirmed by histological analysis. The effective diffusion coefficient determined from the analysis of the kinetics of the diffuse reflectance was found equal to D = (7.5 ± 0.9)10–7 cm2/s for healthy tissue and D = (1.4 ± 0.2)10–6 cm2/s for sarcoma. In healthy tissue, optical clearing occurred with the formation of two UV transparency windows: (18 ± 4) nm wide centered at 225 nm and (50 ± 12) nm wide centered at 375 nm. For the ovary with sarcoma, the formation of only one transparency window centered at 380 nm and a width of (43 ± 11) nm was observed.


ovarian tissues; cancer; glucose; total transmittance spectra; diffuse reflectance spectra; diffusion coefficient; optical clearing efficiency

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