Laser photomodification of insulin solution
DOI:
https://doi.org/10.18287/JBPE19.05.020301Keywords:
crystallogram, image processing, structure monitoring, laser biostimulationAbstract
The article discusses influence of laser radiation on structure of insulin solution. We monitored changes in the structure of insulin solutions by means of analysis of crystallograms with a nanometer resolution probe microscope as well as by correlation processing of speckle patterns obtained by passing laser radiation through the solution. It was experimentally shown that laser radiation promoted solution homogenization by changing size of macromolecular clusters.References
A. V. Kartelishev, A. G. Rumyancev, A. R. Evstigneev, A. V. Geiniz, and S. V. Usova (Eds.), Lazernaya terapiya i profilaktika, Prakticheskaya meditsina, Moscow, Russia (2012) [in Russian]. ISBN 978-5-98811-219-8.
A. M. Enejder, T. W. Koo, J. Oh, M. Hunter, S. Sasic, M. S. Feld, and G. L. Horowitz, “Blood analysis by Raman spectroscopy”, Optics Letters 27(22), 2004-2006 (2002).
A. Rygula, K. Majzner, K. M. Marzec, A. Kaczor, M. Pilarczyk, and M. Baranska, “Raman spectroscopy of proteins: a review”, Journal of Raman Spectroscopy 44(8), 1061-1076 (2013).
G. A. Zalesskaya, E. G. Sambor, “Interaction of low-intensity laser radiation with blood and its components”, Journal of Applied Spectroscopy 72(2), 230-235 (2005) [in Russian].
A. N. Malov, A. Y. Seteikin, A. V. Neupokoeva, E. S. Musatova, I. E. Golub, L. V. Sorokina, V. S. Fetschenko, and A. A. Vaichas, “The laser radiation action on the biological objects”, Optik 124(23), 6034-6041 (2013).
R. A. Paringer, A. V. Kupriyanov, and N. Y. Ilyasova, “Dendritic crystallogram images classification”, Journal of Biomedical Photonics & Engineering 1(2), 135-138 (2015).
A. N. Malov, A. V. Neupokoeva, “A «chessboard» method for the speckle images analysis”, Holography. Science and practice. Collection of works of the 10th International Conference “GoloExpo 2013”, OOO «MNGS», Moscow, 257-264 (2013) [in Russian].
M. A. Vilensky, D. N. Agafonov, D. A. Zimnyakov, V. V. Tuchin, and R. A. Zdrazhevsky, “Speckle-correlation analysis of microcapillary blood flow in the nail bed,” Quantum Electronics 41(4), 324–328 (2011).
S. V. Moskvin, Osnovy lazernoy terapii. Seriya “Effektivnaya lazernaya terapiya,” Triada, Tver (2016) [in Russian].
A. N. Malov, A. V. Neupokoyeva, and L. A. Kokorina, “Laser modification of liquid nutrient medium and antibiotic solutions with the assessment by the bacteria growth dynamics,” The Journal of Biomedical Photonics & Engineering 3(2), 020303 (2017).
Y. Y. Tarasevich, “The models and mechanisms of the dehydration self-organization of biological fluids,” Physics-Uspekhi 47(7), 717-728 (2004).
E. G. Rapis, “A change in the physical state of a nonequilibrium blood plasma protein film in patients with carcinoma,” Technical Physics 47(4), 510-512 (2002).
A. I. Andryushkin, S. P. Sapozhnikov, and A. V. Karpunina, “Crystallography of biological fluids (a review),” Vestnik Chuvashskogo Universiteta 3, 355-359 (2013) [in Russian].
P. V. Pavlov, A. N. Malov, A. V. Neupokoeva, and F. N. Popov, “A testing method for machine details state by means of the speckle image parameters analysis”, Proceedings of SPIE 10176, 101760Z (2016).
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Copyright (c) 2019 Anna V. Neupokoeva, Evgenia A. Kuzina, Nikita S. Moskalev, Anna I. Nikonova, Sergey A. Nebogin

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