Estimating the Porosity of Nickel-Titanium (NiTi) Implants Using Optical Coherence Tomography and Machine Learning
Paper #9177 received 10 Oct 2024; revised manuscript received 27 Oct 2024; accepted for publication 28 Oct 2024; published online 2 Dec 2024.
DOI: 10.18287/JBPE24.10.040310
Abstract
Nickel-titanium (NiTi) implants take root well in the body and have high biocompatibility with respect to surrounding tissues. Porosity is an important parameter responsible for the biocompatibility of the material, and as a result, it is important to be able to control the material manufacturing process to achieve the required values. Destructive and non-destructive methods are currently used to analyse porosity, of which non-destructive ones are the most preferable. A method of estimating the porosity of NiTi materials using optical coherence tomography and machine learning was developed. The trained support vector machine with a radial basis function kernel classifier using the first and the second order statistics of optical coherence tomography images as a feature vector provided the classification accuracy of 95 ± 6% for two classes of NiTi materials.
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1. V. E. Gunther, V. N. Khodorenko, and Y. F. Yasenchuk, Titanium nickelide. A new generation medical material, Publishing House of MIT, Tomsk (2006). ISBN: 5-98589-020-1.
2. M. Saini, Y. Singh, P. Arora, V. Arora, and K. Jain, “Implant biomaterials: a comprehensive review,” World Journal of Clinical Cases 3(1), 52–57 (2015).
3. M. Bahraminasab, B. B. Sahari, “NiTi shape memory alloys, promising materials in orthopedic applications”, Shape Memory Alloys-Processing, Characterization and Applications 261–278 (2013).
4. I. V. Shishkovsky, L. T. Volova, M. V. Kuznetsov, Yu. G. Morozov, and I. P. Parkind, “Porous biocompatible implants and tissue scaffolds synthesized by selective laser sintering from Ti and NiTi,” Journal of Materials Chemistry 18(12), 1309–1317 (2008).
5. J. L. Hernandez, K. A. Woodrow, “Medical applications of porous biomaterials: features of porosity and tissue-specific implications for biocompatibility”, Advanced Healthcare Materials 11(9), 2102087 (2022).
6. Y. Yasenchuk, E. Marchenko, V. Gunther, A. Radkevich, O, Kokorev, S. Gunther, G. Baigonakova, V. Hodorenko, T. Chekalkin, J. Kang, S. Weiss, and A. Obrosov, “Biocompatibility and clinical application of porous tini alloys made by self-propagating high-temperature synthesis (SHS),” Materials 12(15), 2405 (2019).
7. F. J. O’Brien, “Biomaterials & scaffolds for tissue engineering,” Materials Today 14(3), 88–95 (2011).
8. J. Rouquerol, D. Avnir, C. W. Fairbridge, D. H. Everett, J. M. Haynes, N. Pernicone, J. D. F. Ramsay, K. S. W. Sing, and K. K. Unger, “Recommendations for the characterization of porous solids,” Pure and Applied Chemistry 66(8), 1739–1758 (1994).
9. T. M. S. Udenni Gunathilake, Y. C. Ching, K. Y. Ching, C. H. Chuah, and L. C. Abdullah, “Biomedical and microbiological applications of bio-based porous materials: a review,” Polymers 9(5), 160 (2017).
10. H. J. Haugen, S. Bertoldi, “Characterization of morphology—3D and porous structure,” Characterization of Polymeric Biomaterials 21–53 (2017).
11. A. V. Medvedeva, D. M. Mordasov, and M. M. Mordasov, “Classification of methods of control of porous materials,” Transactions TSTU 18(3), 749–753 (2012). [In Russian]
12. E. Widiatmoko, M. Abdullah, and A. Khairurrijal, “Method to measure pore size distribution of porous materials using scanning electron microscopy images,” Aip conference proceedings. American Institute of Physics 1284(1), 23–26 (2010).
13. A. Bansiddhi, T. D. Sargeant, S. I. Stupp, and D. C. Dunand, “Porous NiTi for bone implants: a review,” Acta Biomaterialia 4(4), 773–782 (2008).
14. A. Gh. Podoleanu, “Optical coherence tomography,” Journal of Microscopy 247(3), 209–219 (2012).
15. O. P. Choudhary, P. Choudhary, “Scanning electron microscope: advantages and disadvantages in imaging components,” International Journal of Current Microbiology and Applied Sciences 6(5), 1877–1882 (2017).
16. S. L. Campello, W. P. Dos Santos, V. F.Machado, C. C. B. O. Mota, A. S. L. Gomes, and R. E. de Souza, “Micro-structural information of porous materials by optical coherence tomography,” Microporous and Mesoporous Materials 198, 50–54 (2014).
17. E. Fink, S. Celikovic, R. M. Fraga, J. Remmelgas, J. Rehrl, and J. Khinast, “In-line porosity and hardness monitoring of tablets by means of optical coherence tomography,” International Journal of Pharmaceutics 666, 124808 (2024).
18. M. Ezzahmoulya, A. Elmoutaouakkila, M. Ed-Dhahraouya, H. Khallokb, A. Elouahlib, A. Mazurierc, A. ElAlbanic, and Z. Hatim, “Micro-computed tomographic and SEM study of porous bioceramics using an adaptive method based on the mathematical morphological operations,” Heliyon 5(12), e02557 (2019).
19. B. Y. Tay, C. W. Goh, Y. W. Gu, C. S. Lim, M. S. Yong, M. K. Ho, and M. H. Myint, “Porous NiTi fabricated by self-propagating high-temperature synthesis of elemental powders,” Journal of Materials Processing Technology, 202(1-3), 359–364 (2008).
20. M. Kaya, N. Orhan, and G. Tosun, “The effect of the combustion channels on the compressive strength of porous NiTi shape memory alloy fabricated by SHS as implant material,” Current Opinion in Solid State and Materials Science, 14(1), 21–25 (2010).
21. E. S. Marchenko, Y. F. Yasenchuk, and I. A. Zhukov, “Features of the SHS of porous titanium nickelide,” Educational and Methodical Manual: [for students of physics and mathematics and physics and technology specialties], Tomsk State University Publishing House, Tomsk (2021). [in Russian]
22. Y. V.Kistenev, D. A. Vrazhnov, V. V. Nikolaev, E. A. Sandykova and N. A. Krivova, “Analysis of collagen spatial structure using multiphoton microscopy and machine learning methods,” Biochemistry Moscow 84, 108–123 (2019).
23. R. B. D’Agostino, “An omnibus test of normality for moderate and large sample size,” Biometrika 58, 341–348 (1971).
24. R.B. D’Agostino, E. S. Pearson, “Tests for departure from normality,” Biometrika 60, 613–622 (1973).
25. M. Mehrpouya, A. Gisario, A. Rahimzadeh, M. Nematollahi, K. S. Baghbaderani, and M. Elahinia, “A prediction model for finding the optimal laser parameters in additive manufacturing of NiTi shape memory alloy,” The International Journal of Advanced Manufacturing Technology 105(11), 4691–4699 (2019).
26. S. Parvizi, H. R. Hafizpour, Sb.K. Sadrnezhaad, A. Akhondzadeh, and M. Abbasi Gharacheh, “Neural network prediction of mechanical properties of porous NiTi shape memory alloy,” Powder Metallurgy 54(3), 450–454 (2011).
27. Q. S. Yan, “Prediction of porosity of porous NiTi alloy from processing parameters based on SVR,” Advanced Materials Research 393, 231–235 (2012).
28. L. Mosser, O. Dubrule, and M. J. Blunt, “Reconstruction of three-dimensional porous media using generative adversarial neural networks,” Physical Review E 96(4), 043309 (2017).
29. V. Maitra, J. Shi, and C. Lu, “Robust prediction and validation of as-built density of Ti-6Al-4V parts manufactured via selective laser melting using a machine learning approach,” Journal of Manufacturing Processes 78, 183–201 (2022).
30. T. Kamal, Gouthama, and A. Upadhyaya, “Machine learning based sintered density prediction of bronze processed by powder metallurgy route,” Metals and Materials International 29(6), 1761–1774 (2023).
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