Detritylation by Self-Contained Photoacid Generators on the Base of Substituted Benzo[b]thiophene-2-Carboxanilides under UV-Laser and Lamp Irradiation

Natalia V. Izmailova orcid (Login required)
Tomsk State University of Control Systems and Radioelectronics, Russian Federation

Lubov G. Samsonova orcid
Tomsk State University of Control Systems and Radioelectronics, Russian Federation

Ruslan M. Gadirov orcid
Tomsk State University of Control Systems and Radioelectronics, Russian Federation


Paper #9518 received 16 Feb 2026; revised manuscript received 26 Mar 2026; accepted for publication 31 Mar 2026; published online 28 May 2026

DOI: 10.18287/JBPE26.12.020305

Abstract

New self-contained acid photogenerators based on substituted benzo[b]thiophene-2-carboxanilides were studied under irradiation with the 3rd harmonic of an Nd-YAG laser (355 nm) and an excimer XeCl lamp (308 nm) in toluene and methylene chloride solutions. The quantum yield of phototransformations of compounds during lamp and laser photolysis was estimated for both solvents. A model experiment was carried out using photogenerated acids to remove the dimethoxytrityl group from 5′-O-(4,4′-dimethoxytrityl)-2-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite].

Keywords

acid photogenerators; 6π-electrocyclization; benzo[b]thiophene-2-carboxanilides; laser photolysis; detritylation

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