Average refractive index of tendon as a function of water content

Marina E. Shvachkina (Login required)
Department of Optics and Biophotonics, Faculty of Physics, Saratov State University, Russia

Dmitry D. Yakovlev
Department of Optics and Biophotonics, Faculty of Physics, Saratov State University, Russia

Alexander B. Pravdin
Department of Optics and Biophotonics, Faculty of Physics, Saratov State University, Russia

Dmitry A. Yakovlev
Department of Optics and Biophotonics, Faculty of Physics, Saratov State University, Russia


Paper #3268 received 23 Dec 2017; revised manuscript received 1 Mar 2018; accepted for publication 16 Mar 2015; published online 31 Mar 2018.

DOI: 10.18287/JBPE18.04.010302

Abstract

Experimental data on the dependence of the average refractive index of rat tail tendon (RTT) on water content are reported. Using optical coherence tomography, the average group refractive index (at a wavelength of 930 nm) and cross-section area of rat tail tendon fascicle specimens during their air-drying and rehydration were monitored. The dependence of the average group refractive index of RTT (ng) on the volume fraction of water (Cw) has been found to be nonlinear and to be well approximated by the quadratic polynomial ng = 1.5713 – 0.1969Cw – 0.0328(Cw)2. The reported data are shown to be in good agreement with previously published data for bovine cornea.

Keywords

collagen; tissue; refractive index; water content; hydration

Full Text:

PDF

References


1. S. L. Jacques, “Optical properties of biological tissues: a review,” Physics in Medicine and Biology 58(11), R37-R61 (2013). Crossref

2. F. P. Bolin, L. E. Preuss, R. C. Taylor, and R. J. Ference, “Refractive index of some mammalian tissues using a fiber optic cladding method,” Applied Optics 28(12), 2297-2303 (1989). Crossref

3. G. J. Tearney, M. E. Brezinski, B. E. Bouma, M. R. Hee, J. F. Southern, and J. G. Fujimoto, “Determination of the refractive index of highly scattering human tissue by optical coherence tomography,” Optics Letters 20(21), 2258-2260 (1995). Crossref

4. A. R. Knuettel and M. Boehlau-Godau, “Spatially confined and temporally resolved refractive index and scattering evaluation in human skin performed with optical coherence tomography,” Journal of Biomedical Optics 5(1), 83-93 (2000). Crossref

5. M. Ohmi, Y. Ohnishi, K. Yoden, and M. Haruna, “In vitro simultaneous measurement of refractive index and thickness of biological tissue by the low coherence interferometry,” IEEE Transactions on Biomedical Engineering 47(9), 1266-1270 (2000). Crossref

6. X. Wang, C. Zhang, L. Zhang, L. Xue, and J. Tian, “Simultaneous refractive index and thickness measurements of bio-tissue by optical coherence tomography,” Journal of Biomedical Optics 7(4), 628-632. (2002). Crossref

7. Y. L. Kim, J. T. Walsh Jr, T. K. Goldstick, and M. R. Glucksberg, “Variation of corneal refractive index with hydration,” Physics in Medicine and Biology 49(5), 859-868 (2004). Crossref

8. J. Lai, Z. Li, C. Wang, and A. He, “Effective refractive indices of biological tissues and its experimental determination,” Proceedings of SPIE 5630 (2005). Crossref

9. H. Ding, J. Q. Lu, W. A. Wooden, P. J. Kragel, and X. H. Hu, “Refractive indices of human skin tissues at eight wavelengths and estimated dispersion relations between 300 and 1600 nm,” Physics in Medicine and Biology 51(6), 1479-1489 (2006). Crossref

10. J. Kim, D. P. Dave, C. G. Rylander, J. Oh, and T. E. Milner, “Spatial refractive index measurement of porcine artery using differential phase optical coherence microscopy,” Lasers in Surgery and Medicine 38(10), 955-959 (2006). Crossref

11. J. Sun, S. J. Lee, L. Wu, M. Sarntinoranont, and H. Xie, “Refractive index measurement of acute rat brain tissue slices using optical coherence tomography,” Optics Express 20(2), 1084-1095 (2012). Crossref

12. D. Maciel, S. P. Veres, H. J. Kreuzer, and L. Kreplak, “Quantitative phase measurements of tendon collagen fibres,” Journal of Biophotonics 10(1), 111-117 (2017). Crossref

13. Z. C. Deng, J. Wang, Z. X. Hu, J. C. Mei, and Q. Ye, “Study on the relation between the refractive index of fresh muscle tissue and its water content from 400 to 750 nm,” Journal of Modern Optics 65(4), 451-455 (2017). Crossref

14. A. M. Zysk, S. G. Adie, J. J. Armstrong, M. S. Leigh, A. Paduch, D. D. Sampson, F. T. Nguyen, and S. A. Boppart, “Needle-based refractive index measurement using low-coherence interferometry,” Optics Letters 32(4), 385-387 (2007). Crossref

15. L. Oliveira, A. Lage, M. P. Clemente, and V. V. Tuchin, “Optical characterization and composition of abdominal wall muscle from rat,” Optics and Lasers in Engineering 47(6), 667-672 (2009). Crossref

16. T. K. Biswas and T. M. Luu, “In vivo MR measurement of refractive index, relative water content and T2 relaxation time of various brain lesions with clinical application to discriminate brain lesions,” Internet Journal of Radiology 13(1), 1 (2011). Crossref

17. P. Fratzl, “Collagen: structure and mechanics, an Introduction,” in Collagen, Springer, New York, USA, 1-13 (2008).

18. P. Kannus, “Structure of the tendon connective tissue,” Scandinavian journal of medicine and science in sports 10(6), 312-320 (2000). Crossref

19. H. R. Screen, V. H. Chhaya, S. E. Greenwald, D. L. Bader, D. A. Lee, and J. C. Shelton, “The influence of swelling and matrix degradation on the microstructural integrity of tendon,” Acta Biomaterialia 2(5), 505-513 (2006). Crossref

20. A. A. de Aro, B. de Campos Vidal, and E. R. Pimentel, “Biochemical and anisotropical properties of tendons,” Micron 43(2), 205-214 (2012). Crossref

21. J. Kastelic, A. Galeski, and E. Baer, “The multicomposite structure of tendon,” Connective Tissue Research 6(1), 11-23 (1978). Crossref

22. R. W. D. Rowe, “The structure of rat tail tendon,” Connective Tissue Research 14(1), 9-20 (1985). Crossref

23. V. V. Tuchin, Tissue optics: light scattering methods and instruments for medical diagnosis, SPIE press, Bellingham, Washington (2015). Crossref

24. A. T. Yeh, B. Choi, J. S. Nelson, and B. J. Tromberg, “Reversible dissociation of collagen in tissues,” Journal of Investigative Dermatology 121(6), 1332-1335 (2003). Crossref

25. W. V. Sorin, and D. F. Gray, “Simultaneous thickness and group index measurement using optical low-coherence reflectometry,” IEEE Photonics Technology Letters 4(1), 105-107 (1992). Crossref

26. X. J. Wang, T. E. Milner, M. C. Chang, and J. S. Nelson, “Group refractive index measurement of dry and hydrated type I collagen films using optical low-coherence reflectometry,” Journal of Biomedical Optics 1(2), 212-217 (1996). Crossref

27. Z. Bor, K. Osvay, B. Racz, and G. Szabo, “Group refractive index measurement by Michelson interferometer,” Optics Communications 78(2), 109-112 (1990). Crossref

28. M. Born, and E. Wolf, Principles of optics: electromagnetic theory of propagation, interference and diffraction of light, Cambridge University Press, Cambridge (1999).

29. D. J. Segelstein, The complex refractive index of water, Doctoral dissertation, University of Missouri-Kansas City, Kansas City (1981).

30. F. De Chaumont, S. Dallongeville, N. Chenouard, N. Herve, S. Pop, T. Provoost, V. Meas-Yedid, P. Pankajakshan, T. Lecomte, Y. Le Montagner, T. Lagache, A.Dufour, and J.-C. Olivo-Marin, “Icy: an open bioimage informatics platform for extended reproducible research,” Nature Methods 9(7), 690-696 (2012). Crossref

31. D. M. Maurice, “The structure and transparency of the cornea,” The Journal of Physiology 136(2), 263-286 (1957). Crossref

32. K. M. Meek, N. J. Fullwood, P. H. Cooke, G. F. Elliott, D. M. Maurice, A. J. Quantock, R. S. Wall, and C. R. Worthington, “Synchrotron x-ray diffraction studies of the cornea, with implications for stromal hydration,” Biophysical Journal 60(2), 467-474 (1991). Crossref

33. E. P. Katz, and S. T. Li, “Structure and function of bone collagen fibrils,” Journal of Molecular Biology 80(1), 1-15 (1973). Crossref

34. D. W. Leonard, and K. M. Meek, “Refractive indices of the collagen fibrils and extrafibrillar material of the corneal stroma,” Biophysical Journal 72(3), 1382-1387 (1997). Crossref

35. C. Morin, C. Hellmich, and P. Henits, “Fibrillar structure and elasticity of hydrating collagen: a quantitative multiscale approach,” Journal of Theoretical Biology 317, 384-393 (2013). Crossref

36. S. Hayes, T. White, C. Boote, C. S. Kamma-Lorger, J. Bell, T. Sorenson, N. Terrill, O. Shebanova, and K. M. Meek, “The structural response of the cornea to changes in stromal hydration,” Journal of The Royal Society Interface 14(131), 20170062 (2017). Crossref

37. J. C. Martinez-Anton, and E. Bernabeu, “Spectrogoniometry and the WANTED method for thickness and refractive index determination,” Thin Solid Films 313, 85-89 (1998). Crossref






© 2014-2025 Authors
Public Media Certificate (RUS
). 12+