Laser photoacoustic spectroscopy applications in breathomics
Yury V. Kistenev
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Tomsk State University, Russia
Siberian State Medical University, Tomsk, Russia
Paper #3307 received 25 Nov 2018; accepted for publication 20 Mar 2019; published online 28 Mar 2019.
DOI: 10.18287/JBPE19.05.010303
Abstract
The breathomics approach to express-diagnosis of bronchopulmonary diseases based on spectral analysis of volatile organic compounds in a patient’s exhaled air is discussed. The basic demands and possible technical solutions to laser photoacoustic spectroscopy equipment in a framework of breathomics are presented. An example of differential diagnostics of the set of bronchopulmonary diseases, including lung cancer (LC) patients (N = 9); patients with chronic obstructive pulmonary disease (COPD) (N = 12); patients with pneumonia (N = 11) and a control group of healthy volunteers using breath air analysis by laser photoacoustic spectroscopy and machine learning is presented.
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