Application of Yb,Er:Glass laser radiation for active drug delivery at the treatment of onychomycosis

Andrey V. Belikov; Anastasia D. Tavalinskaya; Sergey N. Smirnov; Andrey N. Sergeev

doi:10.18287/JBPE19.05.010305

Authors

Andrey V. Belikov ITMO University, Saint Petersburg, Russian Federation
Anastasia D. Tavalinskaya ITMO University, Saint Petersburg, Russian Federation
Sergey N. Smirnov ITMO University, Saint Petersburg, Russian Federation
Andrey N. Sergeev ITMO University, Saint Petersburg, Russian Federation

DOI:

https://doi.org/10.18287/JBPE19.05.010305

Keywords:

laser, drug delivery, nail, hydrodynamic effects, treatment of onychomycosis, photodynamic therapy

Abstract

The paper discusses the active delivery of a drug (methylene blue solution) through the Er:YLF-laser-perforated nail plate using pulsed radiation of microsecond Yb,Er:Glass laser. Different methods of laser impact on liquid drug are considered: by focused and diverging laser beam. It was established that both discussed methods can provide sufficient dose of the drug for the treatment of onychomycosis.

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