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Temperature Dependencies of the Aggregation Properties of RBC in Dextran Solutions In Vitro
Petr B. Ermolinskiy
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Department of Physics, M.V. Lomonosov Moscow State University, Russia
International Laser Center, M.V. Lomonosov Moscow State University, Russia
Paper #3372 received 23 May 2020; revised manuscript received 17 Jun 2020; accepted for publication 18 Jun 2020; published online 25 Jun 2020.
DOI: 10.18287/JBPE20.06.020501
Abstract
The process of reversible spontaneous aggregation of red blood cells (RBC), as well as the process of their shear stress induced disaggregation, both affect hemorheology and blood microcirculation in the human body. The aim of this work is to estimate the influence of temperature on the aggregation properties of RBC suspended in PBS dextran solutions in vitro. Laser method based on diffuse light scattering was used to estimate the RBC aggregation properties. The results demonstrate a clear dependence of the critical shear stress aggregation parameter of RBC in PBS dextran solutions on temperature. These results would help to better understand the process of RBC aggregation.
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