Research into Silicon Nanoparticles as Agents for UHF Hyperthermia In Vitro
Paper #3385 received 25 Nov 2020; revised manuscript received 2 Mar 2021; accepted for publication 23 Mar 2021; published online 31 Mar 2021.
DOI: 10.18287/JBPE21.07.010306
Abstract
The current approaches to cancer treatment, including surgery and high-energy beam irradiation, do not always give satisfactory results for a number of oncological neoplasms. One of the promising areas in oncology is the use of nanoparticles selectively heated by external action as agents for hyperthermia of some types of tumors. In this work, we performed selective heating of suspensions of silicon nanoparticles using a device for electromagnetic high-frequency therapy (UHF-60).
Keywords
Full Text:
PDFReferences
1. Y. V. Kargina, A. M. Perepukhov, A. Yu. Kharin, E. A. Zvereva, A. V. Koshelev, S. V. Zinovyev, A. V. Maximychev, A. F. Alykova, N. V. Sharonova, V. P. Zubov, M. V. Gulyaev, Y. A. Pirogov, A. N. Vasiliev, A. A. Ischenko, and V. Yu. Timoshenko, “Silicon Nanoparticles Prepared by Plasma-Assisted Ablative Synthesis: Physical Properties and Potential Biomedical Applications,” Physica Status Solidi (A) 216(14), 1800897 (2019).
2. Y. Zhang, M. Li, X. Gao, Y. Chen, and T. Liu, “Nanotechnology in cancer diagnosis: progress, challenges and opportunities,” Journal of Hematology & Oncology 12(1), 137 (2019).
3. K. Greish, “Enhanced Permeability and Retention (EPR) Effect for Anticancer Nanomedicine Drug Targeting,” in Cancer Nanotechnology. Methods in Molecular Biology (Methods and Protocols), S. Grobnyer, B. Moudgil (Eds.), Humana Press, New Jersey, USA, 25–37 (2010).
4. D. I. Bilenko, O. Y. Belobrovaya, V. V. Galushka, E. A. Zharkova, D. O. Kochnev, I. B. Mysenko, V. P. Polyanskaya, and D. V. Terin, “Porous silicon with AGI nanoparticles is a promising material for biomedical applications,” Methods of computer diagnostics in biology and medicine, 201–203 (2015) [in Russian].
5. Hyperthermia (accessed 13 November 2020). [https://nmicr.ru/meditsina/vysokotekhnologichnaya-meditsinskaya-pomoshch/gipertermiya/].
6. L. A. Osminkina, V. Yu. Timoshenko, “Porous Silicon as a Sensitizer for Biomedical Applications,” Mesoporous Biomaterials 3, 39–48 (2016).
7. K. P. Tamarov, L. A. Osminkina, S. V. Zinovyev, K. A. Maximova, J. V. Kargina, M. B. Gongalsky, Y. Ryabchikov, A. Al-Kattan, A. P. Sviridov, M. Sentis, A. V. Ivanov, V. N. Nikiforov, A. V. Kabashin, and V. Y. Timoshenko, “Radio frequency radiation-induced hyperthermia using Si nanoparticle-based sensitizers for mild cancer therapy,” Scientific reports 4, 7034 (2014).
8. L. T. Canham, “Silicon quantum wire array fabrication by electrochemical and chemical dissolution of wafers,” Applied Physics Letters 57(10), 1046–1048 (1990).
9. Transmission electron microscope LEO 912 ab omega (accessed 18 December 2020). [https://istina.msu.ru/equipment/card/29156772].
10. L. Sancey, S. Kotb, C. Truillet, F. Appaix, A. Marais, E. Thomas, B. van der Sanden, J.-P. Klein, B. Laurent, M. Cottier, R. Antoine, P. Dugourd, G. Panczer, F. Lux, P. Perriat, V. Motto-Ros, and O. Tillement, “Long-Term exvo Clearance of Gadolinium-Based AGuIX Nanoparticles and Their Biocompatibility after Systemic Injection,” ACS Nano 9(3), 2477–2488 (2015).
© 2014-2025 Authors
Public Media Certificate (RUS). 12+