Diagnostics of Oxidative Stress by Laser Optical-Acoustic Spectroscopy

Аndrey А. Boyko
Tomsk State University, Russia

Alexey V. Borisov
Tomsk State University, Russia

Vyacheslav S. Zasedatel
Tomsk State University, Russia

Vyacheslav V. Romanchuk
Tomsk State University, Russia

Yury V. Kistenev (Login required)
Tomsk State University, Russia


Paper #3522 received 10 Sep 2022; revised manuscript received 16 Oct 2022; accepted for publication 17 Oct 2022; published online 12 Dec 2022.

DOI: 10.18287/JBPE22.08.040301

Abstract

The results of the registration of oxidative stress volatile molecular markers (NOx, C2H6, and C5H12) in exhaled air by optical-acoustic spectroscopy are presented. Aerobic physical exercises were chosen as a method of oxidative stress activation. Three time points were studied: before exercises, immediately after exercises, and after 25 min rest. It was shown that there is a statistically significant increase in the studied markers concentrations in the exhaled air immediately after the exercises. After the rest, statistically significant differences are observed in relation to the initial state only for a part of these markers. This is most likely caused by different recovery of the subjects after the exercises and insufficient rest time. Thus, this instrumental approach is promising for non-invasive registration of markers of oxidative stress.

Keywords

oxidative stress; human exhalation analysis; non-invasive diagnostics; optical parametric oscillator; laser optical-acoustic spectroscopy

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