Change of optical properties of hair cells during malignant tumour development

Valeriya S. Maryakhina; Larisa S. Scheglova; Ksenia A. Anenkova

doi:10.18287/jbpe-2015-1-1-59

Authors

Valeriya S. Maryakhina Orenburg State University
Larisa S. Scheglova Orenburg state university, Russian Federation
Ksenia A. Anenkova M. V. Lomonosov Moscow state university, Russian Federation

DOI:

https://doi.org/10.18287/jbpe-2015-1-1-59

Keywords:

breast cancer, hair, optical biomedical diagnostics, dynamic light scattering, fluorescence.

Abstract

The results of experimental investigations on the differences of wool microstructure and its biophysical properties of healthy mice and mice with malignant tumor(s) are represented in the paper. It is shown that destruction of wool structure as well as biochemical composition change of wool cells is during pathology development. Difference is seen even when tumor is small. We have shown that the general regularity of spectral measurements for mammary and hair cells is conserved at health state and pathology present. Taking into account this, the represented data about wool structure can be used to improve the optical techniques for non-invasive diagnostics of cancer diseases at different stages of pathology.

Author Biographies

Valeriya S. Maryakhina, Orenburg State University

Associate professor, senior researcher
Ksenia A. Anenkova, M. V. Lomonosov Moscow state university, Russian Federation

PhD student

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