Low-Coherence Reflectometry and Speckle Polarimetry in the Monitoring of Human Skin Pathologic Changes

Elena M. Artemina (Login required)
Saratov State Medical University named after V.I. Razumovsky, Russia

Sergey A. Yuvchenko
Saratov State Technical University named after Yu.A. Gagarin, Russia

Marina V. Alonova
Saratov State Technical University named after Yu.A. Gagarin, Russia

Dmitry A. Zimnyakov
Saratov State Technical University named after Yu.A. Gagarin, Russia

Sergey R. Utz
Saratov State Medical University named after V.I. Razumovsky, Russia

Paper #3267 received 18 Dec 2017; revised manuscript received 18 Feb 2018; accepted for publication 18 Feb 2018; published online 20 Mar 2018. [Special Section. Workshop “Biophotonics” of the XV all-Russian Youth Samara conference-contest on optics and laser physics].

DOI: 10.18287/JBPE18.04.010501


We present the results of the study of normal and pathologic human skin using low-coherence reflectometry and speckle polarimetry. The statistical characteristics of local polarisation states in the individual coherence areas (speckles) of the forward scattered laser radiation demonstrate high sensitivity to the pathologic changes of the biotissue morphology in vitro. The analysis of the attenuation rate of the low-coherence reflectometer signal depending on the probing depth provides additional information for the identification of skin morphologic changes and the analysis of the effect of immersion agents on the biotissue optical properties.


surface epidermis strip; polarisation diagnostics of biotissues; optical clearing of biotissues; optical coherence tomography

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