Hyperspectral Holography and Laser Diffractometry of Erythrocytes

Andrei E. Lugovtsov; Vladislav D. Ustinov; Georgy S. Kalenkov; Sergey G. Kalenkov; Alexander V. Priezzhev

doi:10.18287/JBPE20.06.020306

Authors

Andrei E. Lugovtsov Department of Physics, M.V. Lomonosov Moscow State University, Russia International Laser Center, M.V. Lomonosov Moscow State University, Russia
Vladislav D. Ustinov Moscow Center of Fundamental and Applied Mathematics, M.V. Lomonosov Moscow State University, Russia
Georgy S. Kalenkov Institute of Geosphere Dynamics (IDG RAS), Moscow, Russia
Sergey G. Kalenkov Moscow Polytechnic University, Moscow, Russia
Alexander V. Priezzhev Department of Physics, M.V. Lomonosov Moscow State University, Russia International Laser Center, M.V. Lomonosov Moscow State University, Russia

DOI:

https://doi.org/10.18287/JBPE20.06.020306

Keywords:

laser diffractometry, hyperspectral holography, erythrocyte, visibility

Abstract

Geometrical 3D models of human red blood cells in dry smear were obtained experimentally using hyperspectral holography technique. Corresponding diffraction patterns in the far field diffraction zone were calculated. Visibility values of the diffraction patterns were obtained in cases of low and high red cell distributions width (RDW). Our study reveals that although the visibility is influenced by the cells shapes, this parameter can still be used to assess red cell distribution width in clinical practice.

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