Magnetic Particle Trapping in a Branched Blood Vessel in the Presence of Magnetic Field

Samia F. Salem; Valery V. Tuchin

doi:10.18287/JBPE20.06.040302

Authors

Samia F. Salem Department of Optics and Biophotonics, Saratov State University, Russia Department of Physics, Faculty of Science, Benha University, Egypt
Valery V. Tuchin Department of Optics and Biophotonics, Saratov State University, Russia Interdisciplinary Laboratory of Biophotonics, National Research Tomsk State University, Russia Laboratory of Molecular Imaging, Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, Russia Institute of Precision Mechanics and Control of the Russian Academy of Sciences, Saratov, Russia

DOI:

https://doi.org/10.18287/JBPE20.06.040302

Keywords:

magnetic nanoparticles, branching vessels, permanent magnet, magnetism, Newtonian fluid, blood vessel, computational modeling

Abstract

This study presents a theoretical model by using the COMSOL Multiphysics^® software to describe the behavior of magnetic nanoparticles through blood stream in a branched blood vessel under the influence of cylindrical permanent magnet that is located outside the vessel. The magnet is placed at one branched vessel to attract the magnetic particles towards targeted locations. The fluid (blood) is assumed being Newtonian; its flow is incompressible and laminar. Magnetic nanoparticles, such as superparamagnetic iron oxide (Fe₃O₄) nanoparticles are used in this theoretical study. The mechanisms of magnetic nanoparticles travelling in the blood stream under influence of a localized static magnetic field are numerically studied. The equations of motion for particles in the flow are governed by a combination of magnetic equations for the permanent magnetic field and the Navier-Stokes equations for fluid.

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