Hide
Show all
Comparative Analysis of Methods of Laser Doppler Flowmetry and Doppler Ultrasound Measurement of Blood Flow during the Procedure of Intermittent Pneumatic Compression
Konstantin V. Mashkov
Saratov National Research State University, Russia
Andrey D. Usanov
Saratov National Research State University, Russia
Rustyam G. Chabbarov
Limited liability company “Omega clinic”, Saratov, Russia
Anatoly V. Skripal
(Login required)
Saratov National Research State University, Russia
Paper #3524 received 17 Oct 2022; revised manuscript received 19 Nov 2022; accepted for publication 12 Dec 2022; published online 24 Dec 2022.
DOI: 10.18287/JBPE22.08.040512
Abstract
The results of the analysis of microcirculation of the blood flow of the toe and ultrasound Doppler measurement of blood flow in the femoral artery during the intermittent pneumatic compression procedure are presented. A professional device “Doctor Life Mark 400” (South Korea) was used for the pressotherapy procedure. Microcirculation was measured using a portable laser Doppler flowmeter “LAZMA PF” (Russia). Ultrasonic Dopplerograms were obtained using the device “Edan U50” (China) with a linear sensor model L15-7b with a frequency in pulsed Doppler mode (PW) 7.2 MHz. The study involved a group of 11 subjects without identified vascular disorders, the age of the group was from 23 to 42 years. The method of calculating the average speed and volume of blood flow over the period of the cardiac cycle was used for ultrasound Dopplerograms. Arterial resistance was evaluated, which was compared with the dynamics of perfusion in the limb. In the studies, approximately half of the test subjects had an increase in perfusion of the microcirculatory bed and a decrease in resistance of arterial vessels. At the same time, with an increase in the perfusion of the microcirculatory bed, a decrease in the resistance of arterial vessels was observed.
Keywords
Full Text:
PDFReferences
1. R. D. Sheldon, B. T. Roseguini,M. H. Laughlin, and S. C. Newcomer, “New insights into the physiologic basis for intermittent pneumatic limb compression as a therapeutic strategy for peripheral artery disease,” Journal of Vascular Surgery 58(6), 1688–1696 (2013).
2. S. J. Kavros, K. T. Delis, N. S. Turner, A. E. Voll, D. A. Liedl, P. Gloviczki, and T. W. Rooke, “Improving limb salvage in critical ischemia with intermittent pneumatic compression: A controlled study with 18-month follow-up,” Journal of Vascular Surgery 47(3), 543–549 (2008).
3. K. T. Delis, G. Slimani, H. M. Hafez, and A. N. Nicolaides, “Enhancing venous outflow in the lower limb with intermittent pneumatic compression. A comparative haemodynamic analysis on the effect of foot vs. calf vs. foot and calf compression,” European Journal of Vascular and Endovascular Surgery 19(3), 250–260 (2000).
4. K. Delis, Z. Azizi, R. Stevens, J. Wolfe, and A. Nicolaides, “Optimum Intermittent Pneumatic Compression Stimulus for Lower-limb Venous Emptying,” European Journal of Vascular and Endovascular Surgery 19(3), 261–269 (2000).
5. K. T. Delis, A. N. Nicolaides, N. Labropoulos, and G. Stansby, “The acute effects of intermittent pneumatic foot versus calf versus simultaneous foot and calf compression on popliteal artery hemodynamics: a comparative study,” Journal of Vascular Surgery 32(2), 284–292 (2000).
6. K. T. Delis, A. N. Nicolaides, J. H. N.Wolfe, and G. Stansby, “Improving walking ability and ankle brachial pressure indices in symptomatic peripheral vascular disease with intermittent pneumatic foot compression: a prospective controlled study with one-year follow-up,” Journal of Vascular Surgery 31(4), 650–661 (2000).
7. N. Labropoulos, L. R. LeonJr, A. Bhatti, S. Melton, S. S. Kang, A. M. Mansour, and M. Borge, “Hemodynamic effects of intermittent pneumatic compression in patients with critical limb ischemia,” Journal of Vascular Surgery 42(4), 710–716 (2005).
8. K. T. Delis, A. L. Knaggs, “Duration and amplitude decay of acute arterial leg inflow enhancement with intermittent pneumatic leg compression: an insight into the implicated physiologic mechanisms,” Journal of Vascular Surgery 42(4), 717–725 (2005).
9. G. Ramaswami, M. D’Ayala, L. H. Hollier, R. Deutsch, and A. J. McElhinney, “Rapid foot and calf compression increases walking distance in patients with intermittent claudication: Results of a randomized study,” Journal of Vascular Surgery 41(5), 794–801 (2005).
10. K. T. Delis, M. J. Husmann, G. Szendro, N. S. Peters, J. H. N. Wolfe, and A. O. Mansfield, “Haemodynamic effect of intermittent pneumatic compression of the leg after infrainguinal arterial bypass grafting,” British Journal of Surgery 91(4), 429–434 (2004).
11. G. Dai, O. Tsukurov, R. W. Orkin, W. M. Abbott, R. D. Kamm, and J. P. Gertler, “An in vitro cell culture system to study the influence of external pneumatic compression on endothelial function,” Journal of Vascular Surgery 32(5), 977–987 (2000).
12. L.-E. Chen, K. Liu, W.-N. Qi, E. Joneschild, X. Tan, A. V. Seaber, J. S. Stamler, and J. R. Urbaniak, “Role of nitric oxide in vasodilation in upstream muscle during intermittent pneumatic compression,” Journal of Applied Physiology 92(2), 559–566 (2002).
13. J. C. Giddings, R. J. Morris, H. M. Ralis, G. M. Jennings, D. A. Davies, and J. P. Woodcock, “Systemic haemostasis after intermittent pneumatic compression. Clues for the investigation of DVT prophylaxis and travellers thrombosis,” Clinical & Laboratory Haematology 26(4), 269–273 (2004).
14. L. A. Killewich, M. A. Cahan, D. J. Hanna, M. Murakami, T. Uchida, L. A. Wiley, and G. C. Hunter, “The effect of external pneumatic compression on regional fibrinolysis in a prospective randomized trial,” Journal of Vascular Surgery 36(5), 953–958 (2002).
15. P. S. Van Bemmelen, J. Weiss-Olmanni, and J. J. Ricotta, “Rapid intermittent compression increases skin circulation in chronically ischemic legs with infra-popliteal arterial obstruction,” VASA. Zeitschrift fur Gefasskrankheiten 29(1), 47–52 (2000).
16. H. Partsch, M. Flour, and P. C. Smith, “Indications for compression therapy in venous and lymphatic disease consensus based on experimental data and scientific evidence under the auspices of the IUP,” International Angiology 27(3), 193–219 (2008).
17. M. Nash, D. Mintz, B. Montalvo, and P. Jacobs, “A randomized blinded comparison of two methods used for venous antistasis in tetraplegia,” The Journal of Spinal Cord Medicine 23(4), 221–227 (2000).
18. R. J. Morris, J. C. Giddings, H. M. Ralis, G. M. Jennings, D. A. Davies, J. P. Woodcock, and F. D. J. Dunstan, “The influence of inflation rate on the hematologic and hemodynamic effects of intermittent pneumatic calf compression for deep vein thrombosis prophylaxis,” Journal of Vascular Surgery 44(5), 1039–1045 (2006).
19. N. Labropoulos, L. R. Leon Jr, A. Bhatti, S. Melton, S. Kang, A. M. Mansour, and M. Borge, “Hemodynamic effects of intermittent pneumatic compression in patients with critical limb ischemia,” Journal of Vascular Surgery 42(4), 710–716 (2005).
20. W. Macaulay, G. Westrich, N. Sharrock, T. P. Sculco, P. H. Jhon, M. G. E. Peterson, and E. A. Salvati, “Effect of pneumatic compression on fibrinolysis after total hip arthroplasty,” Clinical Orthopaedics and Related Research 399, 168–176 (2002).
21. E. Kalodiki, A. D. Giannoukas, “Intermittent pneumatic compression (IPC) in the treatment of peripheral arterial occlusive disease (PAOD)–a useful tool or just another device?” European Journal of Vascular and Endovascular Surgery 33(3), 309–310 (2007).
22. K. T. Delis, M. J. W. Husmann, A. N. Nicolaides, J. H. Wolfe, and N. J. Cheshire, “Enhancing foot skin blood flux in peripheral vascular disease using intermittent pneumatic compression: controlled study on claudicants and grafted arteriopaths,” World Journal of Surgery 26(7), 861–866 (2002).
23. A. J. Comerota, “Intermittent pneumatic compression: physiologic and clinical basis to improve management of venous leg ulcers,” Journal of Vascular Surgery 53(4), 1121–1129 (2011).
24. I. V. Barkhatov, “Assessment of the microcirculation system by laser Doppler flowmetry,” Clinical Medicine 91(11), 21–27 (2013) [in Russian].
25. C. Thorn, A. Shore, “Medical Products Inspired by Biological Oscillators: Intermittent Pneumatic Compression and the Microcirculation,” Physics of Biological Oscillators, 385–399 (2021).
26. A. I. Krupatkin, V. V. Sidorov, Laser Doppler flowmetry of blood microcirculation, Meditcina, Moscow, Russia (2005) [in Russian].
27. E. F. Dutikova, Yu. V. Ziyaeva, Ultrasound examination of the main arteries of the extremities, 2nd ed., Scientific and Practical Center of Medical Radiology of the Department of Health of the City of Moscow, Moscow, Russia (2019) [in Russian].
28. N. D. Sorokina, G. V. Selitcky, O. A. Podgornaya, and A. S. Zherdeva, “The clinical-physiological indices of application of interrupted pneumo-compression in prevention of thrombosis of deep veins and thromboembolism of pulmonary arteries,” Rossiiskii meditsinskii zhurnal 24(1), 29–34 (2018) [in Russian].
29. R. Z. Bakhtiyarov, M. R. Zabirov, “Hypertension and endothelial dysfunction,” Bulletin of Orenburg State University 4(29), 114–118 (2004) [in Russian].
30. B. A. Namakanov, M. M. Rasulov, “Endothelial dysfunction in arterial hypertension - cardiovascular complication risk factor,” Cardiovascular Therapy and Prevention 4(6), 98–101 (2005) [in Russian].
31. S. G. Kasatkina, S. N. Kasatkin, “The meaning of endothelium dysfunction in patients with diabetes mellitus of the second type,” Fundamental Research (7), 248–252 (2011) [in Russian].
32. D. K. Gainullina, O. O. Kiryukhina, and O. S. Tarasova, “Nitric oxide in vascular endothelium: regulation of production and mechanisms of action,” Advances in Physiological Sciences 44(4), 88–102 (2013).
33. A. J. Comerota, “Intermittent pneumatic compression: physiologic and clinical basis to improve management of venous leg ulcers,” Journal of Vascular Surgery 53(4), 1121–1129 (2011).
34. A. M. Melkumyants, T. V. Balakhonova, O. A. Pogorelova, and M. I. Tripoten, “Effect of short-term physical training on hemodynam-ic aspects of endothelial function in human brachial artery,” Cardiological Bulletin 14(3), 44–48 (2019) [in Russian].
35. A. H. Chen, S. G. Frangos, S. Kilaru, and B. E. Sumpio, “Intermittent pneumatic compression devices–physiological mechanisms of action,” European Journal of Vascular and Endovascular Surgery 21(5), 383–392 (2001).
36. K. J. Williams, H. M. Moore, and A. H. Davies, “Haemodynamic changes with the use of neuromuscular electrical stimulation compared to intermittent pneumatic compression,” Phlebology 30(5), 365–372 (2015).
© 2014-2025 Authors
Public Media Certificate (RUS). 12+