The Effect of Photobiostimulation by Light Waves in the Blue Range of the Spectrum on Microcirculation Parameters and the Activity of Oxidative Homeostasis Enzymes in the Skin

Vadim V. Astashov (Login required)
Peoples’ Friendship University of Russia, Moscow, Russia

Valentin I. Kozlov
Peoples’ Friendship University of Russia, Moscow, Russia
Scientific and Practical Center for Laser Medicine named after O. K. Skobelkin, Moscow, Russia

Vladimir A. Duvanskiy
Peoples’ Friendship University of Russia, Moscow, Russia
Scientific and Practical Center for Laser Medicine named after O. K. Skobelkin, Moscow, Russia

Pavel V. Novokreshchenov
Peoples’ Friendship University of Russia, Moscow, Russia

Ilya M. Pushkar
Peoples’ Friendship University of Russia, Moscow, Russia


Paper #3531 received 15 Sept 2022; revised manuscript received 15 Dec 2022; accepted for publication 15 Dec 2022; published online 30 Mar 2023.

DOI: 10.18287/JBPE23.09.010309

Abstract

The study employs laser doppler flowmetry and laser fluorescence spectroscopy to reveal the changes in microcirculation and activity of coenzymes of oxidative metabolism in the finger skin under the influence of photobiostimulation by monochrome incoherent low-intensity electromagnetic radiation with a wavelength of 470 nm. Photobiostimulation with light waves in the blue range has contributed to an increase in hemomicrocirculation during and 15 min after the termination of exposure, while the indicator lymph outflow, on the contrary, decreased during the irradiation period and recovered after its termination. The dynamics of changes within the parameters of blood microcirculation, the lymph flow in microvessels and the indicators of oxidative metabolism showed that the skin microcirculation system is an important acceptor of the photobiostimulating effect of light in the blue range of the spectrum. Photobiostimulation triggers the mechanism of activation of hemomicrocirculation by reducing myogenic vasomotion, thereby increasing the conductivity of cardiogenic biorhythm in the vessels of the microcirculatory bed. With an increase in the level of hemomicrocirculation, photobiostimulation is directly associated with the activation of tissue oxidative metabolism.

Keywords

laser doppler flowmetry; lymph outflow; blood microcirculation; myogenic vasomotion; oxidative metabolism; photobiostimulation with light waves in the blue range of the spectrum

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