Intermolecular Interaction and Complex Formation of Cytoflavin Components: IR Spectroscopy and Molecular Modeling
DOI:
https://doi.org/10.18287/JBPE25.11.020303Keywords:
succinic acid, nicotinamide, inosine, cytoflavin, density functional theory, IR spectrumAbstract
IR spectra of intermolecular complexes of the main active components of cytoflavin: succinic acid, nicotinamide and inosine are analyzed. The study focuses on interpreting the absorption band maxima associated with hydrogen bonding between the key functional groups of cytoflavin’s constituents. The IR spectra were calculated using density functional theory (DFT) with the B3LYP functional, while experimental IR spectra were recorded using the SpectrumTwo FTIR spectrometer. The results showed that succinic acid has the ability to interact effectively with both one and two nicotinamide molecules by forming stable hydrogen bonds, whereas in complexes with inosine, the strength of the hydrogen bonds is weaker. This suggests that inosine acts as a cofactor to increase the overall stability of the complex.References
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